Puremed | Wound Management

Wound healing jumpstarted by stimulation with the patients own white cells and platelets

Our approach to wound healing and wound management is based on a simple, yet very powerful thinking where wound healing is jumpstarted by wound stimulation with the patients own white cells and platelets on the wound bed and via injection stimulation around the edge of the wound.

Our Smart Blood Concentrates solutions A-PRF™ and i-PRF™ are on the verge to break through as the strongest and most efficient way to do wound healing. The processes, the setup and the gain in handling time, shortened healing time and lift in life quality makes A-PRF™ and i-PRF™ wound management solution a simple choice.

A-PRF™ fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

Wound Management | Components

Wound | A-PRF™

A-PRF™ – Advanced Platelet Rich Fibrin

The A-PRF™ fibrin membrane is manufactures chairside based on venous blood drawn from the patient into A-PRF™ tubes. After few minutes of spin in the DUO centrifuge a blood clot is turned into a fibrin membrane encapsulating white cells and platelets for slow release for more than 7 days.

Wound | i-PRF™

i-PRF™ – Injectable Platelet Rich Fibrin

i-PRF is a liquid “fibrin membrane” based on venous blood from the patient and is also created chairside in few minutes. It contains high levels of leucocytes, platelets and some stemcells. i-PRF™ coagulates few minutes after the end of the spin and enable usage via injections and a stable stimulation.

Wound | Epiflex

Epiflex® – human acellular dermis transplant

In wound sites where a graft is needed to rebuild the missing skin layers, Epiflex is a often used solution among physicians and wound care professionals in Germany. Epiflex is a human acellular dermis transplant that is manufactured from skin recovered from screened consenting donors according to validated and approved methods. Combined with A-PRF™ membranes above, integration happens faster.

A-PRF™ fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

A-PRF™ | The process & application

A-PRF™ | Phlebotomy

Venous blood is drawn into A-PRF™ 10 ml tubes. This is done fast and each tube is placed into the centrifuge.

A-PRF™ | Spin

The A-PRF™ tubes are placed into the DUO centrifuge. It can hold 12 tubes. The protocol is pre-programmet and spin the tubes for 8 minutes. After the spin the lit opens and the next step can be performed.

A-PRF™ | Compression

The RBC are removed from the clot and the plasma clot is placed in the PRF box. A double lit is placed on top and in few minutes the exudate is removed from the clot and a each clot is turned into a fibrin membrane.

A-PRF | membrane

Each membrane is approximately 10 x 20 mm in size. If spinning 12 tubes an area of 14 – 20 cm2 may be covered with A-PRF™ membranes. The membrane size may differ from patient to patient.

A-PRF | membrane – wound

Example of how A-PRF™ membranes cover a wound surface.

They stick to the surface easily. The picture to the right is 1 week later

A-PRF | membrane on wound after 1 week