Pure Wound Healing

Puremed | Wound Management

Wound healing jumpstarted by stimulation with the patients own white cells and platelets

Our approach to wound healing and wound management is based on a simple, yet very powerful thinking where wound healing is jumpstarted by wound stimulation with the patients own white cells and platelets on the wound bed and via injection stimulation around the edge of the wound.

Our Smart Blood Concentrates solutions A-PRF™ and i-PRF™ are on the verge to break through as the strongest and most efficient way to do wound healing. The processes, the setup and the gain in handling time, shortened healing time and lift in life quality makes A-PRF™ and i-PRF™ wound management solution a simple choice.

A-PRF™ fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

 

Wound Management | Components

Wound | A-PRF™

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A-PRF™ – Advanced Platelet Rich Fibrin

The A-PRF™ fibrin membrane is manufactures chairside based on venous blood drawn from the patient into A-PRF™ tubes. After few minutes of spin in the DUO centrifuge a blood clot is turned into a fibrin membrane encapsulating white cells and platelets for slow release for more than 7 days.

Wound | i-PRF™

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i-PRF™ – Injectable Platelet Rich Fibrin

i-PRF is a liquid “fibrin membrane” based on venous blood from the patient and is also created chairside in few minutes. It contains high levels of leucocytes, platelets and some stemcells. i-PRF™ coagulates few minutes after the end of the spin and enable usage via injections and a stable stimulation.

Wound | Epiflex

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Epiflex® – human acellular dermis transplant

In wound sites where a graft is needed to rebuild the missing skin layers, Epiflex is a often used solution among physicians and wound care professionals in Germany. Epiflex  is a human acellular dermis transplant that is manufactured from skin recovered from screened consenting donors according to validated and approved methods. Combined with A-PRF™ membranes above, integration happens faster.

A-PRF™ fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

A-PRF™ | The process & application

A-PRF™ | Phlebotomy

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Venous blood is drawn into A-PRF™ 10 ml tubes. This is done fast and each tube is placed into the centrifuge.

A-PRF™ | Spin

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The A-PRF™ tubes are placed into the DUO centrifuge. It can hold 12 tubes. The protocol is pre-programmet and spin the tubes for 8 minutes. After the spin the lit opens and the next step can be performed.

A-PRF™ | Compression

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The RBC are removed from the clot and the plasma clot is placed in the PRF box. A double lit is placed on top and in few minutes the exudate is removed from the clot and a each clot is turned into a fibrin membrane.

A-PRF | membrane

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Each membrane is approximately 10 x 20 mm in size. If spinning 12 tubes an area of 14 – 20 cm2 may be covered with A-PRF™ membranes. The membrane size may differ from patient to patient.

A-PRF | membrane – wound

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Example of how A-PRF™ membranes cover a wound surface.

They stick to the surface easily. The picture to the right is 1 week later

A-PRF | membrane on wound after 1 week

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The same A-PRF™ membranes as on the left picture – now one week later.

Healing result after few days

A-PRF™ Liquid | the new option for large membranes

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane preparation proces step-by-step

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane with significant strength and flexibility

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane placed in box for gentle compression

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane after compression

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane ready to cover wound

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large membrane covering wound

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large round membrane before and after compression

A-PRF™ Liquid | large PRF membranes 

A-PRF™ large round membrane in site and sutured

Wound healing | examples

These examples are for healthcare professionals – click on the section to open each example

Please note that the pictures need to load

Wound | Diabetic foot wound after amputation

Wound | Diabetic foot wound after amputation

Infection for 15 days after amputation. A-PRF™ membrans placed on wound bed and wrapped into a plastic film to avoid the A-PRF™ getting dried out – normal wound dressing used on the outside. Notice the blood vessels after 7 days and note the healing result after 30 days!

Wound | Heel wound

Wound | Heel wound

Heel wound with no healing for 6 month prior to PRF treatment. Notice the blood vessels after 4 days from the PRF treatment start. After 60 days the wound is completely healed. The treatment was done once and the rest was up to the blood vessels.

Wound | Pulpura Fulminans

Wound | Pulpura Fulminans

Severe wound case – prior different technics was used with little success through 1,5 year. Then Dr. Choukroun proposed to use PRF membranes. During one month three sessions of PRF was done starting from the wound margin and towards the center. The treatment was interupted for three months and reinitiated for 1 month.

 

Wound | Tibia on 81 years old woman - part 1

Wound | Tibia on 81 years old woman – part 1

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week A-PRF™ treatment started. The wound is covered by A-PRF™ membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the A-PRF™ membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Tibia on 81 years old woman - part 2

Wound | Tibia on 81 years old woman – part 2

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week A-PRF™ treatment started. The wound is covered by A-PRF™ membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the A-PRF™ membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Tibia on 81 years old woman - part 3

Wound | Tibia on 81 years old woman – part 3

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week A-PRF™ treatment started. The wound is covered by A-PRF™ membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the A-PRF™ membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Osteonecrosis

Wound | Osteonecrosis

 

Wound | Leg wound II

Wound | Leg wound II

 

Wound | Head wound

Wound | Head wound I

 

Wound | Finger trauma

Wound | Finger trauma

 

Wound | Osteonecrosis

 

Wound | infectious Osteomylitis

Wound | infectious Osteomylitis

 

Wound healing | video examples

These examples are for healthcare professionals

Head wound | – 5 days healing

A-PRF™ membranes placed on wound – healing time 5 days

Osteomylitis | grafting process

Process of grafting using bone, A-PRF™ and i-PRF™