Pure Wound Healing

Puremed | Wound Management

Wound healing by stimulation using the patient’s white cells and platelets.

Our approach to wound healing and wound management is based on simple yet compelling thinking where wound healing is jumpstarted by wound stimulation with the patient’s white cells and platelets on the wound bed and via injection stimulation around the margins of the wound.

 

PRF fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

 

Wound Management | Components

Wound | PRF

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PRF – solid Platelet Rich Fibrin

The PRF fibrin membrane is manufactures chairside based on venous blood drawn from the patient into PRF tubes. After few minutes of spin in the centrifuge a blood clot is turned into a fibrin membrane encapsulating white cells and platelets for slow release for more than 7 days.

Wound | injectable PRF

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Liquid Injectable Platelet Rich Fibrin

Injectable PRF is a liquid “fibrin membrane” based on venous blood from the patient and is also created chairside in few minutes. It contains high levels of leucocytes, platelets, and some stem cells. injectable PRF coagulates few minutes after the end of the spin and enable usage via injections and a stable stimulation.

Wound | Epiflex

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Epiflex® – human acellular dermis transplant

In wound sites where a graft is needed to rebuild the missing skin layers, Epiflex is a often used solution among physicians and wound care professionals in Germany. Epiflex  is a human acellular dermis transplant that is manufactured from skin recovered from screened consenting donors according to validated and approved methods. Combined with A-PRF™ membranes above, integration happens faster.

Platelet Rich Fibrin membrans on wound bed for stimulation of the inflammatory cascade and faster healing

PRF | The process & application

PRF | Phlebotomy

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Venous blood is drawn into PRF 10 ml tubes. This is done fast and each tube is placed into the centrifuge.

PRF | Spin

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The PRF tubes are placed into the centrifuge. It can hold 12 tubes. The protocol is pre-programmet and spin the tubes for 8 minutes. After the spin the lit opens and the next step can be performed.

PRF | Compression

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The RBC are removed from the clot and the plasma clot is placed in the PRF box. A double lit is placed on top and in few minutes the exudate is removed from the clot and a each clot is turned into a fibrin membrane.

PRF | membrane

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Each membrane is approximately 10 x 20 mm in size. If spinning 12 tubes an area of 14 – 20 cm2 may be covered with PRF membranes. The membrane size may differ from patient to patient.

PRF | membrane – wound

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Example of how PRF membranes cover a wound surface.

They stick to the surface easily. The picture to the right is 1 week later

PRF | membrane on wound after 1 week

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The same PRF membranes as on the left picture – now one week later.

Healing result after few days

PRF Liquid | the new option for large membranes

Liquid PRF | large PRF membranes 

PRF large membrane preparation proces step-by-step

Liquid PRF | large PRF membranes 

PRF large membrane with significant strength and flexibility

Liquid PRF | large PRF membranes 

Large PRF membrane placed in box for gentle compression

Liquid PRF | large PRF membranes 

Large PRF membrane after compression

Liquid PRF | large PRF membranes 

Large PRF membrane ready to cover wound

Liquid PRF | large PRF membranes 

Large PRF membrane covering wound

Liquid PRF | large PRF membranes 

Large round PRF membrane before and after compression

Liquid PRF | large PRF membranes 

Large round PRF membrane in site and sutured

Wound healing | examples

These examples are for healthcare professionals – click on the section to open each example

Please note that the pictures need to load

Wound | Diabetic foot wound after amputation

Wound | Diabetic foot wound after amputation

Infection for 15 days after amputation. PRF membrans placed on wound bed and wrapped into a plastic film to avoid the PRF getting dried out – normal wound dressing used on the outside. Notice the blood vessels after 7 days and note the healing result after 30 days!

Wound | Heel wound

Wound | Heel wound

Heel wound with no healing for 6 month prior to PRF treatment. Notice the blood vessels after 4 days from the PRF treatment start. After 60 days the wound is completely healed. The treatment was done once and the rest was up to the blood vessels.

Wound | Pulpura Fulminans

Wound | Pulpura Fulminans

Severe wound case – prior different technics was used with little success through 1,5 year. Then Dr. Choukroun proposed to use PRF membranes. During one month three sessions of PRF was done starting from the wound margin and towards the center. The treatment was interupted for three months and reinitiated for 1 month.

 

Wound | Tibia on 81 years old woman - part 1

Wound | Tibia on 81 years old woman – part 1

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Tibia on 81 years old woman - part 2

Wound | Tibia on 81 years old woman – part 2

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Tibia on 81 years old woman - part 3

Wound | Tibia on 81 years old woman – part 2

Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.

Wound | Osteonecrosis

Wound | Osteonecrosis

 

Wound | Leg wound II

Wound | Leg wound II

 

Wound | Head wound

Wound | Head wound I

 

Wound | Finger trauma

Wound | Finger trauma

 

Wound | Osteonecrosis

 

Wound | infectious Osteomylitis

Wound | infectious Osteomylitis

 

Wound healing | video examples

These examples are for healthcare professionals

Head wound | – 5 days healing

PRF membranes placed on wound – healing time 5 days

Osteomylitis | grafting process

Process of grafting using bone, Solid PRF and Liquid PRF