PRF – solid Platelet Rich Fibrin
The PRF fibrin membrane is manufactures chairside based on venous blood drawn from the patient into PRF tubes. After few minutes of spin in the centrifuge a blood clot is turned into a fibrin membrane encapsulating white cells and platelets for slow release for more than 7 days.
Liquid Injectable Platelet Rich Fibrin
Injectable PRF is a liquid “fibrin membrane” based on venous blood from the patient and is also created chairside in few minutes. It contains high levels of leucocytes, platelets, and some stem cells. injectable PRF coagulates few minutes after the end of the spin and enable usage via injections and a stable stimulation.
Epiflex® – human acellular dermis transplant
In wound sites where a graft is needed to rebuild the missing skin layers, Epiflex is a often used solution among physicians and wound care professionals in Germany. Epiflex is a human acellular dermis transplant that is manufactured from skin recovered from screened consenting donors according to validated and approved methods. Combined with A-PRF™ membranes above, integration happens faster.
PRF | Phlebotomy
Venous blood is drawn into PRF 10 ml tubes. This is done fast and each tube is placed into the centrifuge.
PRF | Spin
The PRF tubes are placed into the centrifuge. It can hold 12 tubes. The protocol is pre-programmet and spin the tubes for 8 minutes. After the spin the lit opens and the next step can be performed.
PRF | Compression
The RBC are removed from the clot and the plasma clot is placed in the PRF box. A double lit is placed on top and in few minutes the exudate is removed from the clot and a each clot is turned into a fibrin membrane.
PRF | membrane
Each membrane is approximately 10 x 20 mm in size. If spinning 12 tubes an area of 14 – 20 cm2 may be covered with PRF membranes. The membrane size may differ from patient to patient.
PRF | membrane – wound
Example of how PRF membranes cover a wound surface.
They stick to the surface easily. The picture to the right is 1 week later
PRF | membrane on wound after 1 week
The same PRF membranes as on the left picture – now one week later.
Liquid PRF | large PRF membranes
PRF large membrane preparation proces step-by-step
Liquid PRF | large PRF membranes
PRF large membrane with significant strength and flexibility
Liquid PRF | large PRF membranes
Large PRF membrane placed in box for gentle compression
Liquid PRF | large PRF membranes
Large PRF membrane after compression
Liquid PRF | large PRF membranes
Large PRF membrane ready to cover wound
Liquid PRF | large PRF membranes
Large PRF membrane covering wound
Liquid PRF | large PRF membranes
Large round PRF membrane before and after compression
Liquid PRF | large PRF membranes
Large round PRF membrane in site and sutured
These examples are for healthcare professionals – click on the section to open each example
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Infection for 15 days after amputation. PRF membrans placed on wound bed and wrapped into a plastic film to avoid the PRF getting dried out – normal wound dressing used on the outside. Notice the blood vessels after 7 days and note the healing result after 30 days!
Heel wound with no healing for 6 month prior to PRF treatment. Notice the blood vessels after 4 days from the PRF treatment start. After 60 days the wound is completely healed. The treatment was done once and the rest was up to the blood vessels.
Severe wound case – prior different technics was used with little success through 1,5 year. Then Dr. Choukroun proposed to use PRF membranes. During one month three sessions of PRF was done starting from the wound margin and towards the center. The treatment was interupted for three months and reinitiated for 1 month.
Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.
Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.
Wound on Tibia after fall from stairs. 81 years old woman. Initially treated at the EMR. After 1 week PRF treatment started. The wound is covered by PRF membranes and wrapped into plastic film. Notice the blood vessels after 1 week and notice the presence of the PRF membranes after 1 week. The patient experienced enhanced vascularisation in the area as “getting warm feet”.
These examples are for healthcare professionals
